Longevity One Starter Stack (NMN, Trans-Resveratrol & Apigenin)
Cell One Plus + Calm One
Support NAD+ all day with a simple stack designed for steadier energy, repair, and recovery.
Key Benefits
- check_circle Supports natural energy, recovery, and healthy aging
- check_circle NMN & Resveratrol combined in one convenient capsule
- check_circle Simple daily routine — just 2 products instead of 3
- check_circle Our most popular stack for a reason
- check_circle Save vs buying each separately
Introducing Longevity One Starter Stack (NMN, Trans-Resveratrol & Apigenin)
Support NAD+ all day with a simple stack designed for steadier energy, repair, and recovery.
Dietary Supplement Description
Most people starting a longevity routine want one thing: a clean, coordinated foundation. Not a shelf of bottles. Not a guessing game. A system.
The Longevity One Starter Stack is exactly that — Cell One (NMN) paired with Sirtuin One (trans-resveratrol) for full NAD+ pathway support around the clock.
Why these two together
NMN supports NAD+ levels — the coenzyme behind cellular energy, DNA repair, and metabolic function. Trans-resveratrol activates the sirtuin pathway that uses NAD+. The two compounds work as a system: NMN supplies the fuel, trans-resveratrol turns the engine on. Nearly every published longevity protocol includes both.
What's in the stack
Cell One: 500mg NMN per capsule, ≥99% purity. Daily.
Sirtuin One: 500mg trans-resveratrol per capsule, 98% pure. Daily.
Two bottles, two capsules daily, one clean foundation.
Who it's for
Adults 40+ starting their longevity routine. People who've researched what they should be taking and want the doses that match the trials. Anyone building a system, not adding to clutter.
How to take it
Cell One in the morning. Sirtuin One with a meal that contains fat (it's fat-soluble — a handful of nuts works). Daily consistency over 30 to 90 days is where the compounding lives.
What to expect
Most people notice steadier daytime energy and sharper afternoon focus within two to four weeks. Recovery and cellular resilience improvements typically follow in weeks three through six. The effects are quieter than dramatic — that's the point.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Key Benefits
- Restores declining NAD+ levels while simultaneously activating sirtuin longevity pathways — now in a single 2-in-1 capsule combining NMN and Resveratrol
- Pairs with Calm One (Apigenin) to protect your NAD+ overnight, allowing your body to perform repair and recovery processes that underpin every other longevity benefit
- Supports mitochondrial energy production at the cellular level, helping your body generate sustained focus and vitality
- Promotes healthy DNA repair by fuelling the PARP enzymes responsible for maintaining genomic integrity
- Saves compared to purchasing Cell One Plus and Calm One individually — making consistent, long-term supplementation more affordable
- Every ingredient is third-party tested for purity exceeding 99%, manufactured under strict GMP conditions, and free from gluten, dairy, soy, and artificial additives
Directions
Follow the individual dosing instructions for each product included in this stack. Take with a meal containing healthy fats for optimal absorption. Consistent daily use is important for sustained results.
Ingredients
Cell One Plus — NMN & Resveratrol
- NMN (Nicotinamide Mononucleotide) 250mg
- Trans-Resveratrol 250mg (Polygonum cuspidatum root extract, >98% purity)
- Other: Hypromellose (Capsule), Rice Flour
- Free from: gluten, dairy, soy, artificial colours, artificial preservatives
Calm One — Apigenin
- Apigenin 50mg (Chamomile flower extract)
- Other: Hypromellose (Capsule), Rice Flour
- Free from: gluten, dairy, soy, artificial colours, artificial preservatives
Nutrition Information
Cell One Plus
| Amount Per Serving | % Daily Value |
|---|---|
| β-Nicotinamide Mononucleotide (NMN) (≥99% purity) 500 mg | † |
| Trans-Resveratrol (≥98% purity) 500 mg | † |
Calm One
| Amount Per Serving | % Daily Value |
|---|---|
| Apigenin (from Chamomile Extract, standardized to 98%) 50-100 mg | † |
The Science
Why these three together?
The Longevity One Starter Stack targets three sides of the same coin: restoring NAD+, activating the genes that use it, and protecting it from being broken down too quickly.
How each ingredient works
NMN directly restores NAD+ levels. A clinical trial confirmed significant NAD+ elevation alongside improvements in muscle insulin sensitivity. Yoshino et al., Science, 2021 ↗
Trans-Resveratrol activates SIRT1 — a longevity gene that regulates DNA repair, inflammation, and metabolic efficiency. Harvard research showed SIRT1 activation extends healthspan in mammals, but only when enough NAD+ is available to fuel it.
Apigenin inhibits CD38 — the enzyme identified as the primary driver of age-related NAD+ breakdown. Research showed that blocking CD38 restores NAD+ levels in aged tissue and reverses mitochondrial decline. Chini et al., Nature Metabolism, 2020 ↗
The synergy
This three-part approach addresses the full NAD+ cycle: build it (NMN), use it (Resveratrol + SIRT1), and protect it (Apigenin). Each compound has strong independent evidence, and their mechanisms are complementary — targeting different points in the same biological network for a greater combined effect.
90 days. Full refund. No friction.
At Vitra One, our products should earn their place in your daily routine.
That's why every Vitra One product is backed by a 90-day return policy.
Take it consistently for at least 30 days as part of your routine. Individual experiences vary. If you're not satisfied within 90 days of purchase, contact us — full refund.
No friction. No unnecessary questions.
This policy applies to purchases made through official Vitra One channels. One refund per customer. Shipping fees are non-refundable.
Your Questions Answered
Can I take NMN & Resveratrol and Apigenin together?
Yes. NMN & Resveratrol and Apigenin are commonly stacked and have complementary mechanisms — that's exactly why we paired them in this stack. Take them together with a meal containing healthy fats for optimal absorption.
How is this different from Cell One Plus?
How do I take the Starter Stack?
Can I subscribe?
How long before I notice anything?
Is each component third-party tested?
Customer Reviews
The Right Place to Start
"I'd been researching longevity for months. This bundle was exactly what I wanted to start with."
Foundation Done Right
"Two products, both at trial-grade doses. No more building my own from five bottles."
Steady, Real Improvement
"Six weeks in. Energy is steadier, recovery is faster, focus is sharper. Worth the stack."
Solid Starting Point
"Good doses, clean formulation. The capsules are a bit large but I'd take them anyway."
Cheaper Than Buying Separately
"Bundling saved money and simplified my morning. Two capsules, done."
My Foundational Layer
"Six months in, this is the base of my routine. Everything else stacks on top of these two."
What I'd Build Myself
"I checked the doses against the trials. They match. That's why I'm here."
Worth the Investment
"Premium-priced but the doses are real. Most cheaper NMN products undershoot the trials."
Simple, Effective
"Two capsules in the morning. Steady energy, sharper focus. That's the entire pitch and it delivers."
Quiet, Compounding Foundation
"Two months in, I notice the cumulative effect — not a single-day shift, but a baseline that's quietly moved up."
You May Also Like
Metabolic Support
A versatile antioxidant that works in every part of your body — supporting energy production, healthy blood sugar, and protecting your cells from everyday damage.
Cellular Energy
Your cells' essential energy fuel. CoQ10 levels decline with age — supplementing helps support heart health, natural energy, and faster recovery.
Sleep & Recovery
The most absorbable form of magnesium for better sleep, muscle recovery, and calm. Most adults don't get enough from food alone.
Cellular Defense
Quercetin supports antioxidant defense and cellular resilience when you want more protection in your daily routine.