Alpha Lipoic One - 60 x R-Alpha Lipoic Acid 300mg Capsules

Alpha lipoic acid is unique among antioxidants because it works in both water-soluble and fat-soluble environments — meaning it can protect virtually every tissue in your body. Most antioxidants are limited to one or the other. ALA operates everywhere, and it also recycles other antioxidants like vitamins C and E, glutathione, and CoQ10, extending their protective lifespan.

Beyond antioxidant defence, ALA plays a direct role in mitochondrial energy metabolism. It serves as a cofactor for key enzymes in the citric acid cycle — the metabolic pathway that generates the majority of your cellular energy. Research in Free Radical Biology and Medicine has demonstrated that ALA supplementation improves mitochondrial function and reduces markers of oxidative stress.

ALA has also shown significant promise for metabolic health. Clinical trials published in Diabetes Care found that ALA improved insulin sensitivity and supported healthy blood sugar metabolism in adults with metabolic concerns.

Alpha Lipoic One delivers a clinically relevant dose of R-alpha lipoic acid — the naturally occurring, more bioactive form. Every batch is pharmaceutical-grade, independently third-party tested, and free from gluten, dairy, soy, and artificial additives. Take one capsule daily on an empty stomach for best absorption.

• The only antioxidant that works in both water-soluble and fat-soluble environments — meaning it can protect virtually every cell, tissue, and organ in your body without limitation
• Recycles and regenerates other key antioxidants including vitamins C and E, glutathione, and CoQ10 — extending their protective lifespan and amplifying your overall antioxidant defence network
• Serves as a direct mitochondrial cofactor in the citric acid cycle, supporting the metabolic pathway responsible for generating the majority of your cellular energy production
• Supports healthy insulin sensitivity and glucose metabolism — clinical trials have demonstrated meaningful improvements in blood sugar markers in adults with metabolic concerns
• Crosses the blood-brain barrier to provide neuroprotective antioxidant support, helping defend neurons against the oxidative stress that contributes to age-related cognitive decline
• Uses R-alpha lipoic acid, the naturally occurring and more bioactive form — significantly more potent than the synthetic racemic mixture found in most supplements on the market
• Pharmaceutical-grade R-ALA, independently third-party tested for purity exceeding 99%, and free from gluten, dairy, soy, and artificial additives

Take 1 capsule daily with a meal. Consistent daily use is important for sustained results. Do not exceed the recommended dose.

See Supplement Facts panel for full ingredient details. Other Ingredients: Hypromellose (Capsule), Rice Flour.

What makes Alpha Lipoic Acid special?

Alpha lipoic acid (ALA) is unique because it works in every part of the cell — both water-soluble and fat-soluble environments. It also serves as a cofactor for key mitochondrial enzymes, directly supporting how your cells produce energy.

What does the research say?

ALA is one of the few antioxidants that can regenerate other antioxidants — including glutathione, vitamin C, vitamin E, and CoQ10 — restoring them to their active forms after they've neutralised free radicals. This "network antioxidant" property makes it far more potent than single-pathway compounds.

Research has shown that the R-form of ALA — the naturally occurring enantiomer — achieves substantially higher absorption than the synthetic racemic mixture commonly used in low-grade supplements.

Clinical studies have also found that ALA significantly improved insulin sensitivity and fasting glucose in adults — operating through a distinct AMPK-mediated mechanism that complements berberine and metabolic support compounds.

Why Alpha Lipoic One?

We use R-Alpha Lipoic Acid exclusively — the more bioactive, naturally occurring form — at 300mg per capsule for a research-relevant dose. Independently tested for purity with every batch.