
Longevity All In One Stack
Cell One Plus + Mito One + Autophagy One
Cover energy, mitochondrial renewal, and cellular cleanup in one complete stack built for daily vitality.
Key Benefits
- check_circle Helps renew your cells from the inside out
- check_circle Supports energy production and physical recovery
- check_circle Three compounds targeting different renewal pathways
- check_circle Our most advanced stack for serious results
- check_circle Save 25% compared to buying each separately
Introducing Longevity All In One Stack
Cover energy, mitochondrial renewal, and cellular cleanup in one complete stack built for daily vitality.
What is Longevity All In One Stack?
The ultimate longevity bundle. Three products that cover NAD+ restoration, sirtuin activation, mitochondrial renewal, and cellular cleanup — everything your cells need to perform at their best.
What's Inside
- Cell One Plus (NMN & Resveratrol) — Boosts NAD+ levels and activates the sirtuin longevity enzymes that depend on it — in a single capsule
- Mito One (Urolithin A) — Clears out old, damaged mitochondria and replaces them with healthy ones
- Autophagy One (Spermidine) — Activates your cells' built-in cleanup system to remove waste
How It Works
As you age, NAD+ levels drop, damaged mitochondria accumulate, and cellular waste builds up — slowing your energy and recovery. This stack targets four distinct longevity pathways: NAD+ restoration, sirtuin activation, mitochondrial recycling (mitophagy), and whole-cell cleanup (autophagy).
Key Benefits
- Targets cellular renewal from three distinct angles — NAD+ restoration, mitochondrial biogenesis via Urolithin A, and autophagy activation through Spermidine — for comprehensive anti-aging support
- Enhances mitophagy, the selective recycling of damaged mitochondria, helping your cells maintain a healthy population of energy-producing organelles as you age
- Activates the autophagy pathway by inhibiting the EP300 acetyltransferase, clearing senescent proteins and cellular debris that accumulate with time and impair tissue function
- Restores NAD+ levels that naturally decline by up to 50% between ages 40 and 60, fuelling the enzymatic reactions essential for DNA repair, metabolism, and energy production
- Supports post-exercise recovery by accelerating mitochondrial turnover and reducing the oxidative damage that contributes to prolonged soreness and fatigue after training
- Provides the most advanced cellular renewal protocol in our range — three clinically researched compounds working together at doses validated in peer-reviewed human studies
- All three formulas are manufactured under GMP conditions, independently verified for purity above 99%, and free from gluten, dairy, soy, and artificial preservatives
Directions
Take Cell One Plus and Autophagy One with your morning meal. Take Mito One with food at any time. All ingredients are pharmaceutical-grade and independently tested.
Ingredients
Cell One Plus — NMN & Resveratrol
β-Nicotinamide Mononucleotide (NMN) (≥99% purity) 250mg + Trans-Resveratrol (≥98% purity) 250mg per capsule
Serving: 2 capsules (500mg NMN + 500mg Resveratrol)
Other: Hypromellose (Capsule), Rice Flour
Mito One — Urolithin A
Urolithin A (≥98% purity) 500mg per capsule
Serving: 1-2 capsules (500-1,000mg)
Other: Hypromellose (Capsule), Rice Flour
Autophagy One — Spermidine
Spermidine (from Wheat Germ Extract, standardized) 5mg per capsule
Serving: 1-2 capsules (5-10mg)
Other: Hypromellose (Capsule), Rice Flour
Contains wheat.
Nutrition Information
Cell One Plus
| Amount Per Serving | % Daily Value |
|---|---|
| β-Nicotinamide Mononucleotide (NMN) (≥99% purity) 500 mg | † |
| Trans-Resveratrol (≥98% purity) 500 mg | † |
Mito One
| Amount Per Serving | % Daily Value |
|---|---|
| Urolithin A (≥98% purity) 500-1,000 mg | † |
Autophagy One
| Amount Per Serving | % Daily Value |
|---|---|
| Spermidine (from Wheat Germ Extract, standardized) 5-10 mg | † |
The Science
Why these three together?
The Longevity All In One Stack targets three of the most important hallmarks of ageing: NAD+ decline, mitochondrial dysfunction, and impaired autophagy — the processes your cells depend on for energy, renewal, and waste clearance. López-Otín et al., Cell, 2013 ↗
How each ingredient works
NMN restores NAD+ — the molecule required for over 500 essential reactions in your cells, including DNA repair and longevity gene activation. Yoshino et al., Science, 2021 ↗
Urolithin A activates mitophagy — the process of clearing out damaged mitochondria and replacing them with healthy new ones. A clinical trial confirmed significant improvements in mitochondrial function and muscle health. Andreux et al., Nature Metabolism, 2019 ↗
Spermidine triggers autophagy — your body's cellular recycling system. A 20-year prospective study linked higher spermidine intake to significantly lower all-cause mortality. Kiechl et al., American Journal of Clinical Nutrition, 2018 ↗
The synergy
Energy production, mitochondrial quality control, and cellular waste clearance are deeply interconnected — declining function in one area accelerates decline in the others. By supporting all three simultaneously, this stack addresses cellular ageing at its most fundamental level.
45-Day Satisfaction Guarantee

At Vitra One, we believe our products should earn their place in your daily routine.
That's why every Vitra One product is backed by our 45-Day Satisfaction Guarantee.
We recommend taking your supplement consistently for at least 30 days as part of your routine. Individual experiences may vary. If you're not satisfied within 45 days of purchase, contact us and we'll provide a full refund.
No friction. No unnecessary questions.
This guarantee applies to purchases made through official Vitra One channels. Limit one refund per customer. Shipping fees are non-refundable.
Your Questions Answered
Everything you need to know about the Defence One Stack.
What's included in the Longevity All In One Stack?
The stack includes Cell One Plus (NMN & Resveratrol), Mito One (Urolithin A), and Autophagy One (Spermidine). Together these target NAD+ restoration, sirtuin activation, mitochondrial renewal, and cellular autophagy.
How is this different from buying products individually?
The stack combines four complementary longevity pathways at a savings vs buying each product separately. The compounds are selected to work synergistically — NAD+ and sirtuin activation power the energy your cells need for mitophagy and autophagy.
Customer Reviews
A Focused Stack That Delivers
"I wanted something more targeted than a five-product protocol but more complete than just NMN alone. Defence One hits exactly that spot. Three months in and my energy and recovery are both noticeably better."
Love The Build And Protect Concept
"The logic behind pairing Cell One Plus with Quercetin makes complete sense to me. You're building NAD+ and then giving your cells a defence layer at the same time. I've been on this for six weeks and feel sharper and less run-down post-workout."
Cleaner Recovery Since Starting This
"I exercise five days a week and was looking for antioxidant support that actually worked alongside my longevity routine. Defence One simplified everything. The soreness after hard sessions has reduced and I'm sleeping better too."
Transparent Formulas, Serious Purity
"What keeps me coming back is that both products in this stack are single-ingredient, properly dosed, and third-party tested. No proprietary blends, no filler. The quercetin is 98% pure and the Cell One Plus dose is exactly what the research recommends."
Good Stack, Takes A Few Weeks
"Give it four to six weeks before you judge it. I didn't notice much in the first two weeks but by week five the difference in my afternoon energy and post-gym recovery was clear. Taking off one star only because the quercetin capsules are a little large."
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