Alpha Lipoic One - 60 x R-Alpha Lipoic Acid 300mg Capsules

Alpha lipoic acid is a rare class of antioxidant — one of the few compounds that's both fat-soluble and water-soluble. That means it can support cellular function across nearly every tissue in your body, not just one compartment.

It's also one of the most studied compounds for healthy glucose metabolism, mitochondrial function, and the regeneration of other antioxidants your body uses every day.

Why R-ALA specifically

Alpha lipoic acid exists in two forms — the R-isomer (the natural form your body makes) and the S-isomer (a synthetic by-product). Most cheap supplements use a 50/50 racemic mixture. We use R-ALA — the form with meaningful biological activity. The dose required is also lower because absorption is better.

What ALA does in the body

Alpha lipoic acid acts as a cofactor in the mitochondrial enzymes that turn glucose into energy. It supports healthy blood sugar regulation, mitochondrial function, and the cellular antioxidant network — including the regeneration of glutathione, vitamin C, and vitamin E once they've been used.

Most studies on healthy glucose support and metabolic function have used R-ALA in the 200–600mg daily range. Our 300mg per capsule matches the mid-range of that literature.

What's in each capsule

300mg of R-alpha lipoic acid per capsule. One capsule daily. Hypromellose capsule, no proprietary blends, no synthetic additives.

Who it's for

Adults 40+ building broad antioxidant support into their routine. Anyone working on metabolic flexibility alongside their longevity work. People who already supplement glutathione, vitamin C, or vitamin E and want the cofactor that helps those antioxidants regenerate.

How to take it

One capsule daily, taken on an empty stomach (about 30 minutes before a meal). ALA absorbs best without food, and morning is ideal. Daily consistency over weeks is where the compounding shows.

What to expect

ALA supports cellular function gradually. Most people notice steadier energy and improved post-meal feel within two to four weeks. The broader antioxidant and metabolic benefits build over months of consistent use.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

• The only antioxidant that works in both water-soluble and fat-soluble environments — meaning it can protect virtually every cell, tissue, and organ in your body without limitation
• Recycles and regenerates other key antioxidants including vitamins C and E, glutathione, and CoQ10 — extending their protective lifespan and amplifying your overall antioxidant defence network
• Serves as a direct mitochondrial cofactor in the citric acid cycle, supporting the metabolic pathway responsible for generating the majority of your cellular energy production
• Supports healthy insulin sensitivity and glucose metabolism — clinical trials have demonstrated meaningful improvements in blood sugar markers in adults with metabolic concerns
• Crosses the blood-brain barrier to provide neuroprotective antioxidant support, helping defend neurons against the oxidative stress that contributes to age-related cognitive decline
• Uses R-alpha lipoic acid, the naturally occurring and more bioactive form — significantly more potent than the synthetic racemic mixture found in most supplements on the market
• Pharmaceutical-grade R-ALA, independently third-party tested for purity exceeding 99%, and free from gluten, dairy, soy, and artificial additives

Take 1 capsule daily with a meal. Consistent daily use is important for sustained results. Do not exceed the recommended dose.

See Supplement Facts panel for full ingredient details. Other Ingredients: Hypromellose (Capsule), Rice Flour.

What makes Alpha Lipoic Acid special?

Alpha lipoic acid (ALA) is unique because it works in every part of the cell — both water-soluble and fat-soluble environments. It also serves as a cofactor for key mitochondrial enzymes, directly supporting how your cells produce energy.

What does the research say?

ALA is one of the few antioxidants that can regenerate other antioxidants — including glutathione, vitamin C, vitamin E, and CoQ10 — restoring them to their active forms after they've neutralised free radicals. This "network antioxidant" property makes it far more potent than single-pathway compounds.

Research has shown that the R-form of ALA — the naturally occurring enantiomer — achieves substantially higher absorption than the synthetic racemic mixture commonly used in low-grade supplements.

Clinical studies have also found that ALA significantly improved insulin sensitivity and fasting glucose in adults — operating through a distinct AMPK-mediated mechanism that complements berberine and metabolic support compounds.

Why Alpha Lipoic One?

We use R-Alpha Lipoic Acid exclusively — the more bioactive, naturally occurring form — at 300mg per capsule for a research-relevant dose. Independently tested for purity with every batch.