Quercetin One - 60 x Quercetin 500mg Capsules

Cellular energy production has a cost. Every time your mitochondria turn fuel into ATP, they produce oxidative byproducts. Healthy cells handle the byproducts through antioxidant defense systems. As you age, those defense systems get less efficient and the byproducts accumulate.

Quercetin is one of the most studied flavonoids for supporting that antioxidant defense layer.

Why antioxidant defense matters for longevity

Oxidative stress is a slow tax on cellular function. It accumulates over decades, contributing to the gradual decline that compounds into the visible signs of aging. The body's natural antioxidant systems (glutathione, superoxide dismutase, and others) handle most of it — but they need raw materials, and they work better when supported.

Quercetin acts as a direct antioxidant and supports the body's natural antioxidant enzymes. It also has senolytic properties — meaning it helps the body clear senescent (zombie) cells that have stopped dividing but won't die, and leak inflammatory signals into surrounding tissue.

How Quercetin One works

500mg of quercetin per capsule supports the cellular protection side of the longevity picture. Pairs cleanly with NMN and trans-resveratrol — NAD+ supports cellular energy supply, quercetin supports the protection layer that keeps those cells functioning under stress.

What's in each capsule

500mg of quercetin dihydrate (≥98% purity). One capsule per serving. Hypromellose capsule, rice flour, no proprietary blends, no synthetic additives.

Who it's for

Adults 40+ who already take NMN or another NAD+ support and want to add the antioxidant defense piece. People whose longevity routine has the build side covered and is ready for the protect side. Anyone whose research has pointed them toward quercetin as the next addressable pathway.

How to take it

One capsule daily with a meal that contains fat — quercetin is fat-soluble, and absorption is meaningfully better with food. Morning or with lunch both work. Consistency over months is what matters.

What to expect

Antioxidant support works at the cellular level over weeks and months — not days. Most people don't feel an immediate shift. The compounding benefit shows up as steadier cellular function under stress, faster recovery, and the kind of resilience that's easier to feel a year later.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

• Functions as a senolytic agent — selectively targeting and clearing senescent zombie cells that accumulate with age and drive chronic inflammation throughout your tissues
• Provides potent antioxidant protection by neutralising reactive oxygen species and reducing oxidative damage to DNA, proteins, and lipid membranes at the cellular level
• Stabilises mast cells and modulates histamine release, supporting healthy immune function and respiratory comfort — particularly valuable during seasonal changes
• Inhibits multiple inflammatory pathways including NF-kB and COX-2, helping reduce the chronic low-grade inflammation that accelerates biological ageing
• Enhances the bioavailability and effectiveness of other supplements when taken together — quercetin has been shown to protect and extend the activity of compounds like resveratrol and vitamin C
• Supports cardiovascular health by promoting healthy endothelial function and helping maintain normal blood pressure through its effects on nitric oxide signalling
• Pharmaceutical-grade quercetin in a highly bioavailable form, independently third-party tested for purity exceeding 99%, and free from gluten, dairy, soy, and artificial additives

Take 1 capsule daily with a meal. Consistent daily use is important for sustained results. Do not exceed the recommended dose.

See Supplement Facts panel for full ingredient details. Other Ingredients: Hypromellose (Capsule), Rice Flour.

What is Quercetin?

Quercetin is one of the most studied flavonoids in longevity research — valued for its potent antioxidant properties, anti-inflammatory effects, and emerging role as a senolytic compound that can help clear senescent cells.

What does the research say?

Quercetin was among the first natural compounds identified as a senolytic — selectively targeting the survival pathways that allow damaged, dysfunctional "zombie" cells to persist and drive chronic inflammation. Zhu et al., Aging Cell, 2015 ↗

A subsequent randomised clinical study using quercetin as a senolytic demonstrated measurable reductions in senescent cell burden and improvements in physical function in older adults. Justice et al., EBioMedicine, 2019 ↗

Beyond senolytic activity, quercetin is a potent anti-inflammatory. A comprehensive review confirmed significant reductions in oxidative stress markers and pro-inflammatory cytokines at doses of 500mg or higher. Boots et al., European Journal of Pharmacology, 2008 ↗

Why Quercetin One?

Few natural compounds can target both senescent cells and chronic inflammation. Quercetin does both — making it a versatile addition to any longevity or cellular defence routine. Each capsule delivers 500mg at ≥98% purity, third-party verified.