Mito One - 60 x Urolithin A 500mg Capsules

Your mitochondria are the power plants inside every cell. They convert what you eat into the energy your body actually uses. With age, they get less efficient — more waste, more errors, less output. You feel it as fatigue that doesn't match your effort.

Urolithin A is one of the few compounds shown to directly support mitophagy — the cellular process that clears worn-out mitochondria and replaces them with healthy ones.

What's actually happening in your mitochondria

You have thousands of mitochondria in every cell. The healthy ones produce energy efficiently and quietly. Damaged ones leak waste, produce less ATP, and accumulate over time — particularly after 40. The cellular system that's supposed to clear them, mitophagy, slows with age.

Urolithin A is a postbiotic — a compound your gut bacteria produce from foods like pomegranates and walnuts. The catch: most adults don't produce meaningful amounts naturally. The research suggests around 60% of people are low producers regardless of diet.

How Mito One works

Direct supplementation gives your body what it can't reliably make on its own. Urolithin A supports the mitophagy pathway, helping your cells clear damaged mitochondria and maintain the healthy ones. The published trials used 500–1000mg daily.

What's in each capsule

500mg of high-purity Urolithin A. One capsule per serving. No proprietary blends. No fillers beyond the hypromellose capsule and rice flour.

Who it's for

Adults 40+ who notice their energy doesn't match their effort the way it used to. Endurance trainers and weekend athletes building cellular support into their routine. Anyone whose longevity protocol has the NAD+ side covered and wants to add mitochondrial support.

How to take it

One capsule daily with a meal that contains some fat — Urolithin A is fat-soluble. Morning or evening both work. Consistency over months is what matters.

What to expect

Mitochondrial improvements show up as gradual increases in endurance and faster recovery — particularly between training sessions. Most people notice the difference around weeks four through eight. Sustained daily energy follows.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

• Activates mitophagy — your body's built-in process for identifying and clearing damaged mitochondria so new, healthy ones can take their place
• Improves cellular energy production by renewing the mitochondria that power every cell, helping restore the vitality that naturally declines with age
• Clinically studied in a 2019 JAMA Network Open trial to support mitochondrial function and muscle endurance in older adults within four months
• Bypasses gut microbiome variability — only 40% of people produce enough Urolithin A naturally, making direct supplementation the most reliable approach
• Supports muscle strength and recovery by improving the quality of mitochondria in skeletal muscle, which is especially important as we age
• Produced through precision fermentation for consistent purity and bioavailability, ensuring you get an effective dose in every single capsule
• Addresses one of the nine hallmarks of ageing — mitochondrial dysfunction — making it a cornerstone of any evidence-based longevity protocol

β-Nicotinamide Mononucleotide (NMN) (≥99% purity) 500mg per capsule. Serving: 2 capsules (1,000mg). Other Ingredients: Hypromellose (Capsule), Rice Flour.

What is Urolithin A?

Urolithin A is a natural compound that activates mitophagy — your body's process for clearing out damaged mitochondria and replacing them with healthy new ones. Think of it as a quality control system for your cellular power plants.

What does the research say?

A randomised, placebo-controlled trial showed that Urolithin A significantly improved mitochondrial function in older adults — modulating plasma acylcarnitines, improving mitochondrial gene expression, and supporting muscle health after just a few months. Andreux et al., Nature Metabolism, 2019 ↗

Earlier research first identified Urolithin A as a potent trigger for mitophagy, showing it extended lifespan in lab models and improved muscle function in aged animals. Only about 40% of people naturally produce enough Urolithin A from food alone — making supplementation the most reliable approach. Ryu et al., Nature Medicine, 2016 ↗

Mitochondrial dysfunction is recognised as one of the nine hallmarks of ageing in the landmark classification by López-Otín and colleagues. López-Otín et al., Cell, 2013 ↗

Why Mito One?

Our Urolithin A is produced via precision fermentation for consistent purity and bioavailability — so you get a reliable dose every time.